Ovarian Cancer

Definition of ovarian cancer: Cancer that forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Most ovarian cancers are either ovarian epithelial carcinomas (cancer that begins in the cells on the surface of the ovary) or malignant germ cell tumors (cancer that begins in egg cells).

Introduction

Women have two ovaries, one on each side of the uterus. The ovaries - each about the size of an almond - produce eggs (ova) as well as the female sex hormones estrogen and progesterone. Ovarian cancer is a disease in which normal ovarian cells begin to grow in an uncontrolled, abnormal manner and produce tumors in one or both ovaries.

According to the American Cancer Society, ovarian cancer ranks fifth in cancer deaths among women. It's estimated that about 20,000 women in the United States will develop ovarian cancer this year. About 15,000 deaths from ovarian cancer will occur in American women during that same time frame.

Your chances of surviving ovarian cancer are better if the cancer is found early. But because the disease is difficult to detect in its early stage, only about 20 percent of ovarian cancers are found before tumor growth has spread into adjacent tissues and organs beyond the ovaries. Most of the time, the disease has already advanced before it's diagnosed.

Symptomless ovarian cancer is most often detected during a woman's regular gynecological examination. Your physician will palpitate your ovaries during your pelvic and rectal exam for the presence of ovarian cysts or fibroid tumors. If any abnormalities are noted, he will follow up with further testing which may include an ultrasound and chest X-ray. If further testing is required, a laparoscopy may be performed.

New methods for early screening of ovarian cancer are being investigated including ultrasound in conjunction with a blood test. The blood test may detect an antigen called CA 125 which has been detected in the blood of women with ovarian cancer.

Why is ovarian cancer a "silent" killer?

Ovarian cancer is often called the "silent" killer because many times there are no symptoms until the disease has progressed to an advanced stage. One-third of American women will get some form of cancer in their lifetime and approximately one and one half percent of those cases will be cancer involving one or both ovaries.